Neuropathy Treatments
TESTIMONIALS
Dr. Shaoulian was able to diagnose my problem where others couldn’t.
 
He prescribed a systemic therapy which proved to be quite successful. Once completely debilitated, I feel there is hope.
 
He really helped me. Thanks so much.
 
Mike.C
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CIDP Treatments

Chronic Inflammatory Demyelinating Polyneuropathy

 

CIDP

Causes

Symptoms

Diagnosis

Treatments

Testimonials

Chronic Inflammatory Demyelinating Polyneuropathy has become one of the most treatable forms of neuropathy.  There are currently multiple modalities that we are able to use for the treatment of CIDP.  Since this is an immune mediated neuropathy, where the body is attacking the nerves, treatment of CIDP is aimed at modulating the immune system to stop the attack.  Once the immune system stops attacking the nerves, the nerves could start to regenerate and reverse the symptoms of CIDP. One category of treatment options include immunosuppressant such as cytoxan, Imuran, and CellCept. These medications weaken the immune system so that it doesn't attack the nerves. Another potent treatment option is IVIG which is a pull of antibodies from more than a thousand patients which is infused to the patient. These antibodies protect the nerves of the body from being attacked. The mechanism is complex and is thought to involve multiple pathways. The next option is plasmapharesis. In this process the patient's blood is filtered and the antibodies and proteins that are responsible for attacking the nerves are removed from the blood.

In most patients we are able to see improvement using these treatment options alone or in combination.  In patients in whom these treatment options are not effective, we are using newer treatments.  We are now able to detect certain antibodies that attack the nerves and we have medications that could knock them out. When used properly, these treatment options are very effective with minimal side effects.   In most patients we are able to significantly improve their symptoms even in the most difficult and severe cases. If you have been diagnosed with CIDP, and you are not happy with the results you are getting or you have been told that there is nothing else that can be done, we could help.

  • Treating CIDP includes prednisone, immunosuppressant drugs, physical therapy, and even plasma exchange and intravenous immunoglobulin therapies.

  • Surgical and orthopedics are required for sural nerve biopsy and in dealing with joint deformities.

 

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References

  1. R. A. C. Hughes, P. Bouche, et al. European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society, European Journal of Neurology 2006, 13: 326–332
  2. J.R. Mendell, MD, R.J. Barohn, MD, et al. Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. Neurology February 27, 2001 vol. 56 no. 4 445-449
  3. Man Mohan Mehndiratta and Avinash Chandra Singh. Plasmapheresis for chronic inflammatory demyelinating polyradiculoneuropathy. Current Allergy and Asthma Reports Volume 7, Number 4, 274-279, DOI: 10.1007/s11882-007-0041-z

 

Neurology Muscular Dystrophy and Neuropathy Specialist
9301 Wilshire Blvd. Suite 600, Beverly Hills (Los Angeles County), CA 90210
(310) 278-2525