Symptoms of CIDP - Chronic Inflammatory Demyelinating Polyneuropathy

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The symptoms of Chronic Inflammatory Demyelinating Polyneuropathy include numbness, tingling, burning and weakness, generally occurring in the feet first and they gradually ascend to involve other parts of the body.  One of the first signs that could develop is a foot drop, where patients develope weakness in their ankles and as a result tend to trip over their feet, or they could develop numbness and tingling in the feet and toes which gradually spreads to to the other parts of the body.  Other organs could also become involved including inability to adequately empty the bladder, nausea, vomiting, abdominal fullness or bloating, diarrhea, or constipation, low blood with dizziness, or trouble maintaining an erection.  The severity and the combination of symptoms vary.  Some could have only numbness and tingling only, others could have weakness only.  Some patients are severely affected and they could become completely paralyzed and have severe numbness and tingling.  Others have a very slow progression with mild disease.  These patients often complain of difficulty with walking.  They develop poor balance and cannot walk for long periods of time.

References

1. R. A. C. Hughes, P. Bouche, et al. European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society, European Journal of Neurology 2006, 13: 326–332
2. J.R. Mendell, MD, R.J. Barohn, MD, et al. Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. Neurology February 27, 2001 vol. 56 no. 4 445-449
3. Man Mohan Mehndiratta and Avinash Chandra Singh. Plasmapheresis for chronic inflammatory demyelinating polyradiculoneuropathy. Current Allergy and Asthma Reports Volume 7, Number 4, 274-279, DOI: 10.1007/s11882-007-0041-z