The initial symptoms of carpal tunnel syndrome are hand numbness, tingling, and burning. Initially the symptoms occur intermittently and worst at night time while the patient is sleeping. The tingling often wakes up the patient, and they have to shake their hands to get rid of it. As the disease progresses the frequency and the intensity of the tingling and burning increases, eventually the symptoms become constant and severe. As the carpal tunnel syndrome gets worst the patient can develop symptoms of weakness and paralysis of the fingers and the hands.